Compound Q&A

How is Methyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrole-3-carboxylate (CAS: 1268619-58-4) typically synthesized?

Answer

Methyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrole-3-carboxylate
Methyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrole-3-carboxylate (CAS: 1268619-58-4) is synthesized through the coupling of 1H-pyrrole-3-carboxylic acid methyl ester and bis(pinacolato)diboron in the presence of a palladium catalyst and a base. The reaction yields a high purity product with excellent selectivity and yield.

About

English Name Methyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrole-3-carboxylate
Molecular Formula C12H18BNO4
Molecular Weight 251.09099999999995 g/mol
SMILES COC(=O)c1c[nH]c(c1)B2OC(C)(C)C(C)(C)O2
InChIKey BSVMPMYZRFLSEK-UHFFFAOYSA-N
Last Updated: 2026-03-20 02:47

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