Compound Q&A
How is 5'-O-[(4-Methylphenyl)sulfonyl]thymidine (CAS: 7253-19-2) typically synthesized?
Answer
![5'-O-[(4-Methylphenyl)sulfonyl]thymidine](https://static.chemtradehub.com/structs/725/7253-19-2-6094.webp "5'-O-[(4-Methylphenyl)sulfonyl]thymidine")
5'-O-[(4-Methylphenyl)sulfonyl]thymidine is typically synthesized via a sulfonylation reaction of thymidine using a sulfonyl chloride derivative in the presence of a base. The reaction is carried out in an inert solvent, and the product has high selectivity and good yield.
About
CAS No
7253-19-2
English Name
5'-O-[(4-Methylphenyl)sulfonyl]thymidine
Molecular Formula
C17H20N2O7S
Molecular Weight
396.42 g/mol
SMILES
CC1=CC=C(C=C1)S(=O)(=O)OCC2C(CC(O2)N3C=C(C(=O)NC3=O)C)O
InChIKey
RSEWNGNFIIXLHN-RRFJBIMHSA-N
Last Updated: 2026-03-19 20:21
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