Compound Q&A
How is 3-(chloromethyl)pyridin-2-amine (CAS: 858431-29-5) typically synthesized?
Answer
3-(Chloromethyl)pyridin-2-amine is typically synthesized via the reaction of 3-chloromethylpyridine with primary amines in the presence of a base. Commonly used bases include sodium hydride or potassium hydroxide. This method provides good yield and high selectivity. The reaction proceeds via nucleophilic substitution, yielding the desired amine compound.
About
CAS No
858431-29-5
English Name
3-(chloromethyl)pyridin-2-amine
Molecular Formula
C6H7ClN2
Molecular Weight
142.589 g/mol
SMILES
NC1=NC=CC=C1CCl
InChIKey
LFZLYRMLFKINJA-UHFFFAOYSA-N
Last Updated: 2026-03-19 14:17
