Compound Q&A

How is ACTH (2-24) (human, bovine, rat) (CAS: 67654-32-4) typically synthesized?

Answer

ACTH (2-24) (human, bovine, rat)
ACTH (2-24) (human, bovine, rat) (CAS: 67654-32-4) is synthesized via solid-phase peptide synthesis. Commonly, the synthesis involves coupling amino acids in a sequential manner using Fmoc chemistry. The peptide is then cleaved from the resin and purified using HPLC. The overall yield for this synthesis is around 70-80%.

About

CAS No 67654-32-4
English Name ACTH (2-24) (human, bovine, rat)
Molecular Formula C134H207N39O29S
Molecular Weight 2860.39 g/mol
SMILES S(C)CCC(C(NC(CCC(=O)O)C(NC(CC1=CNC=N1)C(NC(CC1C=CC=CC=1)C(NC(CCCNC(=N)N)C(NC(CC1=CNC2C=CC=CC1=2)C(NCC(NC(CCCCCN)C(N1CCCC1C(NC(C(NCC(NC(CCCCN)C(NC(CCCCN)C(NC(CCCNC(=N)N)C(NC(CCCNC(=N)N)C(N1CCCC1C(NC(C(NC(C(NC(C(NC(CC1C=CC(=CC=1)O)C(N1CCCC1C(=O)O)=O)=O)C(C)C)=O)CCCCN)=O)C(C)C)=O)=O)=O)=O)=O)=O)=O)C(C)C)=O)=O)=O)=O)=O)=O)=O)=O)=O)NC(C(CO)NC(C(CC1C=CC(=CC=1)O)N)=O)=O
InChIKey UCMABAPARYUDEN-UHFFFAOYSA-N
Last Updated: 2026-03-19 14:17

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