Compound Q&A

How is 2-Methyl-2-propanyl 4-{[5,6-dimethoxy-2-(methoxycarbonyl)-1-oxo-2,3-dihydro-1H-inden-2-yl]methyl}-1-piperidinecarboxylate (CAS: 652130-41-1) typically synthesized?

Answer

2-Methyl-2-propanyl 4-{[5,6-dimethoxy-2-(methoxycarbonyl)-1-oxo-2,3-dihydro-1H-inden-2-yl]methyl}-1-piperidinecarboxylate
2-Methyl-2-propanyl 4-{[5,6-dimethoxy-2-(methoxycarbonyl)-1-oxo-2,3-dihydro-1H-inden-2-yl]methyl}-1-piperidinecarboxylate is synthesized through a multi-step process involving the condensation of 2-(methoxycarbonyl)-5,6-dimethoxy-1-oxo-2,3-dihydro-1H-indene-2-carboxylic acid and 2-methyl-2-propanyl 1-piperidinecarboxylate. The synthesis typically requires the use of a Lewis acid catalyst and proceeds with high selectivity, yielding a product with an excellent yield of up to 90%.

About

English Name 2-Methyl-2-propanyl 4-{[5,6-dimethoxy-2-(methoxycarbonyl)-1-oxo-2,3-dihydro-1H-inden-2-yl]methyl}-1-piperidinecarboxylate
Molecular Formula C24H33NO7
Molecular Weight 447.53 g/mol
SMILES CC(C)(C)OC(=O)N1CCC(CC1)CC2(CC3=CC(=C(C=C3C2=O)OC)OC)C(=O)OC
InChIKey GOKDAFHFQHDFNX-UHFFFAOYSA-N
Last Updated: 2026-03-17 15:30

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