How is Benzyl [(1R,3S)-3-aminocyclohexyl]carbamate (CAS: 1932063-48-3) typically synthesized?

Benzyl [(1R,3S)-3-aminocyclohexyl]carbamate is typically synthesized by reacting benzyl isocyanate with 3-amino-cyclohexanol. The reaction occurs under mild conditions, often in the presence of a base such as triethylamine to enhance the nucleophilicity of the amino group. The yield is generally high, and the reaction is selective, leading to a single diastereomer of the product.