Compound Q&A

How is 2-Isobutylpyridine (CAS: 6304-24-1) typically synthesized?

Answer

2-Isobutylpyridine
2-Isobutylpyridine is usually synthesized via a Grignard reaction using isobutyl magnesium bromide and 2-pyridinecarboxaldehyde. This method provides a high yield and good selectivity, making it a preferred route for industrial production. Another method involves the reaction of 2-pyridinecarboxaldehyde with isobutyl lithium under anhydrous conditions.

About

CAS No 6304-24-1
English Name 2-Isobutylpyridine
Molecular Formula C9H13N
Molecular Weight 135.21 g/mol
SMILES CC(C)Cc1ccccn1
InChIKey BBVSPSDWPYWMOR-UHFFFAOYSA-N
Last Updated: 2026-03-16 21:46

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