Compound Q&A

How is 9-(biphenyl-3-yl)-carbazol-3-yl boronic acid (CAS: 1416814-68-0) typically synthesized?

Answer

9-(biphenyl-3-yl)-carbazol-3-yl boronic acid
9-(biphenyl-3-yl)-carbazol-3-yl boronic acid can be synthesized via a Suzuki coupling reaction using 3-bromo-9-carbazolylbenzene and biphenyl-3-ylboronic acid as reactants. Palladium(II) acetate and tri-ortho-tolylphosphine (Pd(OAc)₂/PrPh₃) are often used as catalysts, with sodium carbonate as a base. The reaction typically proceeds at 80°C, yielding a high purity compound with good selectivity.

About

English Name 9-(biphenyl-3-yl)-carbazol-3-yl boronic acid
Molecular Formula C24H18BNO2
Molecular Weight 363.22 g/mol
SMILES OB(c1ccc2c(c1)c1ccccc1n2c1cccc(c1)c1ccccc1)O
InChIKey ALTSSZFRWDVXPB-UHFFFAOYSA-N
Last Updated: 2026-03-16 17:23

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