Compound Q&A
How is N-[(2S)-1-Amino-3-methyl-1-oxo-2-butanyl]-1-(4-fluorobenzyl)-1H-indazole-3-carboxamide (CAS: 1185282-01-2) typically synthesized?
Answer
![N-[(2S)-1-Amino-3-methyl-1-oxo-2-butanyl]-1-(4-fluorobenzyl)-1H-indazole-3-carboxamide](https://static.chemtradehub.com/structs/118/1185282-01-2-0336.webp "N-[(2S)-1-Amino-3-methyl-1-oxo-2-butanyl]-1-(4-fluorobenzyl)-1H-indazole-3-carboxamide")
N-[(2S)-1-Amino-3-methyl-1-oxo-2-butanyl]-1-(4-fluorobenzyl)-1H-indazole-3-carboxamide is typically synthesized through multi-step reactions involving benzylamine, fluoroaniline, and indazole derivatives. Commonly, a palladium-based catalyst is used to facilitate the cross-coupling reaction, leading to high selectivity and yield. Protective group techniques and purification methods are employed to ensure the quality of the final product.
About
CAS No
1185282-01-2
English Name
N-[(2S)-1-Amino-3-methyl-1-oxo-2-butanyl]-1-(4-fluorobenzyl)-1H-indazole-3-carboxamide
Molecular Formula
C20H21FN4O2
Molecular Weight
368.41 g/mol
SMILES
CC([C@@H](C(=O)N)NC(=O)c1nn(c2c1cccc2)Cc1ccc(cc1)F)C
InChIKey
AKOOIMKXADOPDA-KRWDZBQOSA-N
Last Updated: 2026-03-16 17:23