Compound Q&A
How is 2-Nitro-4-(trifluoromethyl)benzamide (CAS: 22227-55-0) typically synthesized?
Answer
2-Nitro-4-(trifluoromethyl)benzamide is typically synthesized through the reaction of 4-(trifluoromethyl)benzoic acid with nitrous acid. The reaction is carried out under controlled conditions to ensure high selectivity and yield. Commonly, amines or amides are used as nucleophiles to introduce the nitro group, and the reaction is monitored using spectroscopic techniques for optimal conditions.
About
CAS No
22227-55-0
English Name
2-Nitro-4-(trifluoromethyl)benzamide
Molecular Formula
C8H5F3N2O3
Molecular Weight
234.13 g/mol
SMILES
C1=CC(=C(C=C1C(F)(F)F)[N+](=O)[O-])C(=O)N
InChIKey
LIDIBDAQJHIRBO-UHFFFAOYSA-N
Last Updated: 2026-03-16 17:23
