Compound Q&A
How is 1-Ethyl 5-(2-methyl-2-propanyl) 3-{[4-(4-methyl-1-piperazinyl)benzoyl]amino}-4,6-dihydropyrrolo[3,4-c]pyrazole-1,5-dicarboxylate (CAS: 761443-69-0) typically synthesized?
Answer
![1-Ethyl 5-(2-methyl-2-propanyl) 3-{[4-(4-methyl-1-piperazinyl)benzoyl]amino}-4,6-dihydropyrrolo[3,4-c]pyrazole-1,5-dicarboxylate](https://static.chemtradehub.com/structs/761/761443-69-0-e14f.webp "1-Ethyl 5-(2-methyl-2-propanyl) 3-{[4-(4-methyl-1-piperazinyl)benzoyl]amino}-4,6-dihydropyrrolo[3,4-c]pyrazole-1,5-dicarboxylate")
This compound is synthesized via a multi-step process involving the condensation of an amino acid derivative with an appropriate acid chloride. The reaction is catalyzed by a Lewis acid and proceeds with good regioselectivity. The yield is typically around 70-80%, and the final product is purified by recrystallization from a suitable solvent.
About
CAS No
761443-69-0
English Name
1-Ethyl 5-(2-methyl-2-propanyl) 3-{[4-(4-methyl-1-piperazinyl)benzoyl]amino}-4,6-dihydropyrrolo[3,4-c]pyrazole-1,5-dicarboxylate
Molecular Formula
C25H34N6O5
Molecular Weight
498.58 g/mol
SMILES
CCOC(=O)N1C2=C(CN(C2)C(=O)OC(C)(C)C)C(=N1)NC(=O)C3=CC=C(C=C3)N4CCN(CC4)C
InChIKey
YLYRHIITRIEACU-UHFFFAOYSA-N
Last Updated: 2026-03-16 13:10
![1-Ethyl 5-(2-methyl-2-propanyl) 3-{[4-(4-methyl-1-piperazinyl)benzoyl]amino}-4,6-dihydropyrrolo[3,4-c]pyrazole-1,5-dicarboxylate — Jin Jinle (Hunan) Chemical Co., Ltd.](https://static.chemtradehub.com/suppliers/67ce76192b2de6e8e95a464e/67ce76192b2de6e8e95a464e-logo.webp){kind=logo}
![1-Ethyl 5-(2-methyl-2-propanyl) 3-{[4-(4-methyl-1-piperazinyl)benzoyl]amino}-4,6-dihydropyrrolo[3,4-c]pyrazole-1,5-dicarboxylate — JiangSuAiKangShengWuYiYaoYanFa Co Ltd](https://static.chemtradehub.com/suppliers/67cec9452b2de6e8e95a52fa/67cec9452b2de6e8e95a52fa-logo.webp){kind=logo}
![1-Ethyl 5-(2-methyl-2-propanyl) 3-{[4-(4-methyl-1-piperazinyl)benzoyl]amino}-4,6-dihydropyrrolo[3,4-c]pyrazole-1,5-dicarboxylate — Shanghai Yuyeh Biotechnology Co., Ltd.](https://static.chemtradehub.com/suppliers/67ce9f132b2de6e8e95a48fe/67ce9f132b2de6e8e95a48fe-logo.webp){kind=logo}