Compound Q&A

How is 4-Methyl-4-phenyl-2-pentanone (CAS: 7403-42-1) typically synthesized?

Answer

4-Methyl-4-phenyl-2-pentanone
4-Methyl-4-phenyl-2-pentanone (CAS: 7403-42-1) is commonly synthesized via the reaction of methyl acetoacetate with phenylmagnesium bromide followed by acid work-up. The yield is typically around 70-80%, with high selectivity towards the desired product.

About

CAS No 7403-42-1
English Name 4-Methyl-4-phenyl-2-pentanone
Molecular Formula C12H16O
Molecular Weight 176.26 g/mol
SMILES CC(=O)CC(c1ccccc1)(C)C
InChIKey PFDVPCSDZXZDMF-UHFFFAOYSA-N
Last Updated: 2026-03-11 07:58

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