Compound Q&A

How is 4-Chloro-6-(methoxymethyl)-2-(3-methylphenyl)pyrimidine (CAS: 438249-83-3) typically synthesized?

Answer

4-Chloro-6-(methoxymethyl)-2-(3-methylphenyl)pyrimidine
4-Chloro-6-(methoxymethyl)-2-(3-methylphenyl)pyrimidine is typically synthesized via a multi-step process involving the reaction of 3-methyl-1,2-diaminobenzene with methanol under mild conditions, followed by chlorination. The exact conditions are critical for yield and purity, and catalysts such as hydrochloric acid are often used. The final product is purified to achieve high selectivity and yield.

About

English Name 4-Chloro-6-(methoxymethyl)-2-(3-methylphenyl)pyrimidine
Molecular Formula C13H13ClN2O
Molecular Weight 248.71 g/mol
SMILES CC1=CC(C2=NC(COC)=CC(Cl)=N2)=CC=C1
InChIKey OWBBPBAWAUMHEO-UHFFFAOYSA-N
Last Updated: 2026-03-10 23:59

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