Compound Q&A

How is [(2R,5R)-5-Methyl-2-piperazinyl]methanol hydrochloride (CAS: 1403898-63-4) typically synthesized?

Answer

[(2R,5R)-5-Methyl-2-piperazinyl]methanol hydrochloride (1:1)
[(2R,5R)-5-Methyl-2-piperazinyl]methanol hydrochloride can be synthesized by reacting 5-methyl-2-piperazinol with hydrochloric acid. The reaction is typically carried out in an aqueous medium, and the product is isolated by crystallization. This method provides good yield and good selectivity for the desired enantiomer.

About

English Name [(2R,5R)-5-Methyl-2-piperazinyl]methanol hydrochloride (1:1)
Molecular Formula C6H15ClN2O
Molecular Weight 166.65 g/mol
SMILES C[C@@H]1CN[C@H](CN1)CO.Cl
InChIKey UGGSBYLNJZDGHG-KGZKBUQUSA-N
Last Updated: 2026-03-10 19:33

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