What regulatory guidelines apply to Axitinib Impurity 1 (CAS: 885126-40-9)?

The regulation of Axitinib Impurity 1 (CAS: 885126-40-9) is guided by various regulatory bodies such as REACH in the EU, the EPA in the USA, and the FDA. These require strict adherence to safety data sheets, hazard communication standards, and proper labeling. Additionally, this impurity must comply with Good Manufacturing Practices (GMP) and International Council for Harmonization (ICH) guidelines to ensure its quality and safety in pharmaceutical manufacturing and research.