Compound Q&A
How is 1-[(1R,4S)-7,7-Dimethyl-2-oxobicyclo[2.2.1]hept-1-yl]methanesulfonamide (CAS: 72597-34-3) typically synthesized?
Answer
![1-[(1R,4S)-7,7-Dimethyl-2-oxobicyclo[2.2.1]hept-1-yl]methanesulfonamide](https://static.chemtradehub.com/structs/725/72597-34-3-eda0.webp "1-[(1R,4S)-7,7-Dimethyl-2-oxobicyclo[2.2.1]hept-1-yl]methanesulfonamide")
1-[(1R,4S)-7,7-Dimethyl-2-oxobicyclo[2.2.1]hept-1-yl]methanesulfonamide is synthesized through the methylation of 7,7-dimethylbicyclo[2.2.1]heptan-2-one using methanesulfonyl chloride in the presence of a base like triethylamine. The reaction is typically carried out in a solvent such as dichloromethane or toluene. The yield is usually around 70-80%, with good selectivity.
About
CAS No
72597-34-3
English Name
1-[(1R,4S)-7,7-Dimethyl-2-oxobicyclo[2.2.1]hept-1-yl]methanesulfonamide
Molecular Formula
C10H17NO3S
Molecular Weight
231.32 g/mol
SMILES
CC1(C2CCC1(C(=O)C2)CS(=O)(=O)N)C
InChIKey
SBLUNABTQYDFJM-XVKPBYJWSA-N
Last Updated: 2026-03-08 04:51
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