Compound Q&A

How is (2S,5R,6R)-6-({(2R)-2-[({2-[(Carboxycarbonyl)(ethyl)amino]ethyl}carbamoyl)amino]-2-phenylacetyl}amino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid (CAS: 64844-70-8) typically synthesized?

Answer

(2S,5R,6R)-6-({(2R)-2-[({2-[(Carboxycarbonyl)(ethyl)amino]ethyl}carbamoyl)amino]-2-phenylacetyl}amino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
The compound is often synthesized via multi-step reactions involving peptide coupling and amide formation. Commonly, a protected amino acid is coupled to a linker, followed by coupling with an activated carboxylic acid derivative. High-yield methods typically use standard protecting group chemistry and are catalyzed with moderate to strong bases under anhydrous conditions.

About

CAS No 64844-70-8
English Name (2S,5R,6R)-6-({(2R)-2-[({2-[(Carboxycarbonyl)(ethyl)amino]ethyl}carbamoyl)amino]-2-phenylacetyl}amino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
Molecular Formula C23H29N5O8S
Molecular Weight 535.58 g/mol
SMILES CCN(CCNC(=O)N[C@H](C1=CC=CC=C1)C(=O)N[C@H]1[C@H]2SC(C)(C)[C@H](C(O)=O)N2C1=O)C(=O)C(O)=O
InChIKey YXRSTHOXBOCROS-BKEDOTJMSA-N
Last Updated: 2026-03-08 04:51

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