Compound Q&A

How is 6-Ethyl-2,2-dimethyl-4H-1,3-dioxin-4-one (CAS: 72324-46-0) typically synthesized?

Answer

6-Ethyl-2,2-dimethyl-4H-1,3-dioxin-4-one
6-Ethyl-2,2-dimethyl-4H-1,3-dioxin-4-one (CAS: 72324-46-0) is commonly synthesized via a multistep process involving the protection of a hydroxyl group, followed by alkylation and subsequent deprotection. Common synthesis methods include the use of acetyl chloride as the acylating agent and sodium hydride as the base. The overall yield is around 70-80%, with high selectivity for the desired product.

About

CAS No 72324-46-0
English Name 6-Ethyl-2,2-dimethyl-4H-1,3-dioxin-4-one
Molecular Formula C8H12O3
Molecular Weight 156.18 g/mol
SMILES CCC1=CC(=O)OC(O1)(C)C
InChIKey BHYAGWPOZQFMQF-UHFFFAOYSA-N
Last Updated: 2026-03-08 00:27

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