Compound Q&A

How is 1-Cyclopropyl-7-[4-(ethoxycarbonyl)-1-piperazinyl]-6-fluoro-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid (CAS: 93594-29-7) typically synthesized?

Answer

1-Cyclopropyl-7-[4-(ethoxycarbonyl)-1-piperazinyl]-6-fluoro-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid
This compound can be synthesized through a multi-step process involving condensation reactions, amidation, and fluorination. Commonly, it is synthesized using 6-fluoroquinoline, ethoxycarbonyl piperazine, and a catalyst such as triethylamine. The overall yield is around 75%.

About

CAS No 93594-29-7
English Name 1-Cyclopropyl-7-[4-(ethoxycarbonyl)-1-piperazinyl]-6-fluoro-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid
Molecular Formula C20H22FN3O5
Molecular Weight 403.41 g/mol
SMILES CCOC(=O)N1CCN(CC1)c2cc3n(cc(C(=O)O)c(=O)c3cc2F)C4CC4
InChIKey SIZQHYOHXHCYHI-UHFFFAOYSA-N
Last Updated: 2026-03-07 19:49

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