Compound Q&A

How is 4,4'-(2,5-Difluoro-1,4-phenylene)dipyridine (CAS: 1429342-59-5) typically synthesized?

Answer

4,4'-(2,5-Difluoro-1,4-phenylene)dipyridine
4,4'-(2,5-Difluoro-1,4-phenylene)dipyridine is synthesized through the coupling of 2,5-difluorophenylpyridine derivatives with themselves using a palladium catalyst in the presence of a base like triphenylphosphine. The reaction yields a high purity product with good selectivity and moderate to good yield.

About

English Name 4,4'-(2,5-Difluoro-1,4-phenylene)dipyridine
Molecular Formula C16H10F2N2
Molecular Weight 268.27 g/mol
SMILES FC1C=C(C2C=CN=CC=2)C(F)=CC=1C1C=CN=CC=1
InChIKey AIOCLFOJLLFDOQ-UHFFFAOYSA-N
Last Updated: 2026-03-07 19:49

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