Compound Q&A
How is 2-[(Cyanomethyl)sulfanyl]-N-[(5aR,6S)-6-methoxy-1,7-dioxo-1,4,6,7-tetrahydro-3H,5aH-azeto[2,1-b]furo[3,4-d][1,3]thiazin-6-yl]acetamide (CAS: 70993-70-3) typically synthesized?
Answer
![2-[(Cyanomethyl)sulfanyl]-N-[(5aR,6S)-6-methoxy-1,7-dioxo-1,4,6,7-tetrahydro-3H,5aH-azeto[2,1-b]furo[3,4-d][1,3]thiazin-6-yl]acetamide](https://static.chemtradehub.com/structs/709/70993-70-3-a3db.webp "2-[(Cyanomethyl)sulfanyl]-N-[(5aR,6S)-6-methoxy-1,7-dioxo-1,4,6,7-tetrahydro-3H,5aH-azeto[2,1-b]furo[3,4-d][1,3]thiazin-6-yl]acetamide")
This compound is typically synthesized via a multistep process involving the coupling of a cyanomethyl sulfide with a 1,4,6,7-tetrahydro-3H,5aH-azeto[2,1-b]furo[3,4-d][1,3]thiazin-6-ol derivative. The reaction is catalyzed by a palladium compound and a ligand under mild conditions, achieving high selectivity and yield. The detailed synthetic route and conditions are found in the literature.
About
CAS No
70993-70-3
English Name
2-[(Cyanomethyl)sulfanyl]-N-[(5aR,6S)-6-methoxy-1,7-dioxo-1,4,6,7-tetrahydro-3H,5aH-azeto[2,1-b]furo[3,4-d][1,3]thiazin-6-yl]acetamide
Molecular Formula
C13H13N3O5S2
Molecular Weight
355.39 g/mol
SMILES
CO[C@]1(NC(=O)CSCC#N)[C@H]2SCC3=C(N2C1=O)C(=O)OC3
InChIKey
GOWIXGITSXCYTK-OLZOCXBDSA-N
Last Updated: 2026-03-07 19:49
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