Compound Q&A
How is Telmisartan sodium (CAS: 515815-47-1) typically synthesized?
Answer
Telmisartan sodium is synthesized through multistep organic reactions. The key steps include the coupling of an aromatic amine with a carboxylic acid followed by a condensation reaction. The process typically uses palladium catalysts and involves protecting groups to enhance selectivity and yield. The final product is obtained with a yield of approximately 70-80%.
About
CAS No
515815-47-1
English Name
Telmisartan sodium
Molecular Formula
C33H29N4NaO2
Molecular Weight
536.59900 g/mol
SMILES
CCCC1=NC2=C(N1CC3=CC=C(C=C3)C4=CC=CC=C4C(=O)[O-])C=C(C=C2C)C5=NC6=CC=CC=C6N5C.[Na+]
InChIKey
RSGAIWOEJXRYRV-UHFFFAOYSA-M
Last Updated: 2026-03-07 15:41