Compound Q&A
How is (1S,4R)-4-(3,4-Dichlorophenyl)-N-methyl-1,2,3,4-tetrahydro-1-naphthalenamine (CAS: 79836-45-6) typically synthesized?
Answer
(1S,4R)-4-(3,4-Dichlorophenyl)-N-methyl-1,2,3,4-tetrahydro-1-naphthalenamine can be synthesized through the reaction of 3,4-dichloroaniline with 1-naphthylmagnesium bromide followed by a Grignard reaction. The process involves the use of a catalyst and proceeds with high selectivity to yield the desired product with a good yield of up to 75-85%.
About
CAS No
79836-45-6
English Name
(1S,4R)-4-(3,4-Dichlorophenyl)-N-methyl-1,2,3,4-tetrahydro-1-naphthalenamine
Molecular Formula
C17H17Cl2N
Molecular Weight
306.24 g/mol
SMILES
CNC1CCC(C2=CC=CC=C12)C3=CC(=C(C=C3)Cl)Cl
InChIKey
VGKDLMBJGBXTGI-PXAZEXFGSA-N
Last Updated: 2026-03-05 12:33
