Compound Q&A

How is (2S,3R)-methyl 3-hydroxy-2-(methylamino)butanoate (CAS: 95599-23-8) typically synthesized?

Answer

(2S,3R)-methyl 3-hydroxy-2-(methylamino)butanoate
(2S,3R)-methyl 3-hydroxy-2-(methylamino)butanoate can be synthesized using a multi-step process involving the condensation of methylamine and 2-hydroxybutanoic acid. The reaction typically requires a solid-phase support and a catalytic amount of a base such as sodium hydroxide. The product is isolated through recrystallization and purification, yielding high selectivity and a high yield of around 85%.

About

CAS No 95599-23-8
English Name (2S,3R)-methyl 3-hydroxy-2-(methylamino)butanoate
Molecular Formula C6H13NO3
Molecular Weight 147.17 g/mol
SMILES CC(C(C(=O)OC)NC)O
InChIKey BZTAVCVTBAXONH-UHNVWZDZSA-N
Last Updated: 2026-03-05 06:57

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