Compound Q&A

How is 8-fluoro-2-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole (CAS: 64368-85-0) typically synthesized?

Answer

8-fluoro-2-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole
8-Fluoro-2-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole is typically synthesized through multi-step processes, involving protection of the indole ring, introduction of the fluoro group, and subsequent ring expansion. Commonly used catalysts include Lewis acids and transition metal complexes. The overall yield is moderate to good, with high selectivity towards the desired product.

About

CAS No 64368-85-0
English Name 8-fluoro-2-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole
Molecular Formula C12H13FN2
Molecular Weight 204.248 g/mol
SMILES CN1CCC2=C(C1)C3=C(N2)C=CC(=C3)F
InChIKey PXCCYWKGOYWGFS-UHFFFAOYSA-N
Last Updated: 2026-03-05 06:57

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