Compound Q&A

How is 3-Ethyl-2-methyl-5-(4-morpholinylmethyl)-1,5,6,7-tetrahydro-4H-indol-4-one (CAS: 7416-34-4) typically synthesized?

Answer

3-Ethyl-2-methyl-5-(4-morpholinylmethyl)-1,5,6,7-tetrahydro-4H-indol-4-one
3-Ethyl-2-methyl-5-(4-morpholinylmethyl)-1,5,6,7-tetrahydro-4H-indol-4-one (CAS: 7416-34-4) is typically synthesized through a multi-step process involving the condensation of an appropriate indole derivative with 4-(morpholinomethyl)benzaldehyde. The reaction is catalyzed by a Lewis acid such as aluminum chloride. The yield is around 65%, and the selectivity is high, making the target compound the major product.

About

CAS No 7416-34-4
English Name 3-Ethyl-2-methyl-5-(4-morpholinylmethyl)-1,5,6,7-tetrahydro-4H-indol-4-one
Molecular Formula C16H24N2O2
Molecular Weight 276.38 g/mol
SMILES CCC1=C(NC2=C1C(=O)C(CC2)CN3CCOCC3)C
InChIKey KLPWJLBORRMFGK-UHFFFAOYSA-N
Last Updated: 2026-03-05 06:57

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