Compound Q&A

How is 5-Bromo-N-methyl-1H-pyrrolo[2,3-b]pyridine-3-carboxamide (CAS: 872620-93-4) typically synthesized?

Answer

5-Bromo-N-methyl-1H-pyrrolo[2,3-b]pyridine-3-carboxamide
5-Bromo-N-methyl-1H-pyrrolo[2,3-b]pyridine-3-carboxamide is typically synthesized via a multi-step process involving bromination and amidation. The key steps include brominating a precursor pyridine derivative followed by condensation with an appropriate amine. The synthesis requires careful control of reaction conditions to ensure high yield and selectivity. Common catalysts and reagents include N,N'-carbonyldiimidazole and N,N-dimethylformamide (DMF).

About

English Name 5-Bromo-N-methyl-1H-pyrrolo[2,3-b]pyridine-3-carboxamide
Molecular Formula C9H8BrN3O
Molecular Weight 254.09 g/mol
SMILES O=C(NC)C1=CNC2=NC=C(Br)C=C12
InChIKey UTJJZKBWXLYEJU-UHFFFAOYSA-N
Last Updated: 2026-03-05 02:11

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