Compound Q&A
How is 4-Amino-1(2H)-isoquinolinone (CAS: 78886-53-0) typically synthesized?
Answer
4-Amino-1(2H)-isoquinolinone is typically synthesized through a condensation reaction of 1-(2-aminoethyl)isoquinoline with hydrochloric acid under reflux conditions. This method yields a high purity product with good selectivity and a yield of around 75-85%. Other routes include the reduction of 1,2-dichloro-isoquinoline with sodium borohydride.
About
CAS No
78886-53-0
English Name
4-Amino-1(2H)-isoquinolinone
Molecular Formula
C9H8N2O
Molecular Weight
160.18 g/mol
SMILES
Nc1c[nH]c(=O)c2ccccc12
InChIKey
VMLHPUMZIKVELK-UHFFFAOYSA-N
Last Updated: 2026-03-05 02:11
