Compound Q&A
How is N-[(2S,3S,5S)-5-Amino-3-hydroxy-1,6-diphenyl-2-hexanyl]-2-(2,6-dimethylphenoxy)acetamide (CAS: 192725-49-8) typically synthesized?
Answer
![N-[(2S,3S,5S)-5-Amino-3-hydroxy-1,6-diphenyl-2-hexanyl]-2-(2,6-dimethylphenoxy)acetamide](https://static.chemtradehub.com/structs/192/192725-49-8-8641.webp "N-[(2S,3S,5S)-5-Amino-3-hydroxy-1,6-diphenyl-2-hexanyl]-2-(2,6-dimethylphenoxy)acetamide")
N-[(2S,3S,5S)-5-Amino-3-hydroxy-1,6-diphenyl-2-hexanyl]-2-(2,6-dimethylphenoxy)acetamide (CAS: 192725-49-8) is typically synthesized via a multi-step process involving the condensation of a 2-(2,6-dimethylphenoxy)acetyl chloride with (2S,3S,5S)-5-amino-3-hydroxy-1,6-diphenyl-2-hexanol. The reaction is catalyzed by a Lewis acid and proceeds with good selectivity and yield, usually around 85-90%.
About
CAS No
192725-49-8
English Name
N-[(2S,3S,5S)-5-Amino-3-hydroxy-1,6-diphenyl-2-hexanyl]-2-(2,6-dimethylphenoxy)acetamide
Molecular Formula
C28H34N2O3
Molecular Weight
446.59 g/mol
SMILES
CC1=C(C(=CC=C1)C)OCC(=O)NC(CC2=CC=CC=C2)C(CC(CC3=CC=CC=C3)N)O
InChIKey
LWXUXIDLCWPHIW-GSDHBNRESA-N
Last Updated: 2026-03-05 02:11
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