Compound Q&A

How is 3-(2,5-Difluorophenyl)-3-oxopropanenitrile (CAS: 71682-96-7) typically synthesized?

Answer

3-(2,5-Difluorophenyl)-3-oxopropanenitrile
3-(2,5-Difluorophenyl)-3-oxopropanenitrile is synthesized through a multi-step process involving the formation of an ester followed by a nitrile formation. The key steps include the conversion of a 2,5-difluorophenyl ester to the corresponding nitrile using a catalyst like sodium hydride. The process typically yields 80-90% in terms of purity and yield, with high selectivity for the desired product.

About

CAS No 71682-96-7
English Name 3-(2,5-Difluorophenyl)-3-oxopropanenitrile
Molecular Formula C9H5F2NO
Molecular Weight 181.14 g/mol
SMILES C1=CC(=C(C=C1F)C(=O)CC#N)F
InChIKey MRKQEVHBBWQIAD-UHFFFAOYSA-N
Last Updated: 2026-03-05 02:11

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