Compound Q&A
How is tert-Butyl 3-(trifluoromethyl)-7,8-dihydro-1,6-naphthyridine-6(5H)-carboxylate (CAS: 624734-26-5) typically synthesized?
Answer
tert-Butyl 3-(trifluoromethyl)-7,8-dihydro-1,6-naphthyridine-6(5H)-carboxylate can be synthesized via an esterification reaction of 3-(trifluoromethyl)-7,8-dihydro-1,6-naphthyridine-6(5H)-carboxylic acid with tert-butyl alcohol in the presence of a catalytic amount of a strong acid like trifluoroacetic acid. The reaction typically yields a high percentage of the target compound with good selectivity.
About
CAS No
624734-26-5
English Name
tert-Butyl 3-(trifluoromethyl)-7,8-dihydro-1,6-naphthyridine-6(5H)-carboxylate
Molecular Formula
C14H17F3N2O2
Molecular Weight
302.3 g/mol
SMILES
CC(C)(C)OC(=O)N1CCC2=C(C1)C=C(C=N2)C(F)(F)F
InChIKey
MSYVHAWMHWYFEB-UHFFFAOYSA-N
Last Updated: 2026-03-05 02:11
