Compound Q&A

How is rac-(1R,5S)-bicyclo[3.2.0]hept-2-en-6-one, cis (CAS: 71155-05-0) typically synthesized?

Answer

rac-(1R,5S)-bicyclo[3.2.0]hept-2-en-6-one, cis
Rac-(1R,5S)-bicyclo[3.2.0]hept-2-en-6-one, cis is typically synthesized via a Wittig reaction, where an alkyl phosphonate is reacted with a cyclic ketone. The use of a chiral auxiliary can provide enantioselective synthesis. The reaction is carried out under mild conditions, and the yield can be up to 90%. The use of a Lewis acid catalyst, such as aluminum trichloride, is often employed to enhance reactivity and selectivity.

About

CAS No 71155-05-0
English Name rac-(1R,5S)-bicyclo[3.2.0]hept-2-en-6-one, cis
Molecular Formula C7H8O
Molecular Weight 108.14 g/mol
SMILES C1C=CC2C1C(=O)C2
InChIKey LNLLHUHPGPKRBM-WDSKDSINSA-N
Last Updated: 2026-03-04 16:30

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