Compound Q&A
Are there alternatives to (3R,5S)Posaconazole in synthesis?
Answer
There are several isomers and analogs of (3R,5S)Posaconazole used in synthesis, such as (3S,5R)-epoxyposaconazole and (3S,5S)-epoxyposaconazole. Common alternative reagents include azoles like fluconazole and itraconazole, which can serve as starting materials or intermediates in the synthesis of posaconazole. However, these alternatives may require different reaction conditions and may not be as effective as posaconazole in certain applications.
About
CAS No
1229428-90-3
English Name
(3R,5S)Posaconazole
Molecular Formula
C37H42F2N8O4
Molecular Weight
700.79 g/mol
SMILES
C(N1N=CN=C1)[C@]1(C2C=CC(F)=CC=2F)OC[C@@H](COC2C=CC(N3CCN(C4C=CC(N5C=NN([C@H](CC)[C@@H](O)C)C5=O)=CC=4)CC3)=CC=2)C1
InChIKey
RAGOYPUPXAKGKH-KTRXSZHWSA-N
Last Updated: 2026-03-03 01:43
