Compound Q&A

How is 9,11beta-Epoxy-17-hydroxy-16beta-methyl-3,20-dioxo-9beta-pregna-1,4-diene-21-yl acetate (CAS: 912-38-9) typically synthesized?

Answer

9,11beta-Epoxy-17-hydroxy-16beta-methyl-3,20-dioxo-9beta-pregna-1,4-diene-21-yl acetate
The compound is typically synthesized via a multi-step process involving the formation of a pregnenolone derivative, followed by epoxidation, hydroxylation, and acetylation reactions. The key reagents used include bromoacetic acid, sodium hypochlorite, and acetic anhydride. The process often requires the use of palladium catalysts and involves careful control of reaction conditions to achieve high selectivity and yield.

About

CAS No 912-38-9
English Name 9,11beta-Epoxy-17-hydroxy-16beta-methyl-3,20-dioxo-9beta-pregna-1,4-diene-21-yl acetate
Molecular Formula C24H30O6
Molecular Weight 414.4980000000002 g/mol
SMILES CC1CC2C3CCC4=CC(=O)C=CC4(C35C(O5)CC2(C1(C(=O)COC(=O)C)O)C)C
InChIKey MONKXVNQUJNHLQ-LGLNQOIUSA-N
Last Updated: 2026-03-01 18:39

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