Compound Q&A

How is 1,3,5-Tri-O-benzoyl-2-O-methyl-alpha-D-ribofuranose (CAS: 68045-07-8) typically synthesized?

Answer

1,3,5-Tri-O-benzoyl-2-O-methyl-alpha-D-ribofuranose
1,3,5-Tri-O-benzoyl-2-O-methyl-alpha-D-ribofuranose (CAS: 68045-07-8) is typically synthesized through a multistep process involving the protection of the hydroxyl groups of ribose with benzoyl groups and subsequent methylation of the 2-hydroxyl position. The synthesis involves the use of acylating agents and protecting groups, with high selectivity and good overall yield. Common catalysts include imidazole and triethylamine.

About

CAS No 68045-07-8
English Name 1,3,5-Tri-O-benzoyl-2-O-methyl-alpha-D-ribofuranose
Molecular Formula C27H24O8
Molecular Weight 476.48 g/mol
SMILES COC1C(C(OC1OC(=O)C2=CC=CC=C2)COC(=O)C3=CC=CC=C3)OC(=O)C4=CC=CC=C4
InChIKey BTKQRBSDABCRCX-DVAKJLRASA-N
Last Updated: 2026-03-01 18:39

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