Compound Q&A
How is 1-Methyl-7-nitro-1H-indazole (CAS: 58706-36-8) typically synthesized?
Answer
1-Methyl-7-nitro-1H-indazole is typically synthesized via the nitration of 1-methyl-1H-indazole. This involves treating 1-methyl-1H-indazole with a nitric acid mixture under reflux conditions. The reaction can be catalyzed by sulfuric acid, and the yield is generally around 70-80%. The nitration step is exothermic and requires careful temperature control to prevent side reactions.
About
CAS No
58706-36-8
English Name
1-Methyl-7-nitro-1H-indazole
Molecular Formula
C8H7N3O2
Molecular Weight
177.16 g/mol
SMILES
CN1N=CC2=C1C(=CC=C2)N(=O)=O
InChIKey
HLSOBULFCLIDKE-UHFFFAOYSA-N
Last Updated: 2026-03-01 17:12
