Compound Q&A

How is 1-(2-(alpha-(p-Chlorophenyl)-alpha-methylbenzyloxy)ethyl)piperidine (CAS: 72869-69-3) typically synthesized?

Answer

1-(2-(alpha-(p-Chlorophenyl)-alpha-methylbenzyloxy)ethyl)piperidine
1-(2-(alpha-(p-Chlorophenyl)-alpha-methylbenzyloxy)ethyl)piperidine is typically synthesized through a multistep process involving the coupling of chlorophenyl group with a piperidine ring via a series of substitution reactions. The synthesis involves the use of protecting groups and catalysts to achieve high selectivity and yield. Common reagents include benzyl chlorides and piperidine derivatives, with yields ranging from 60% to 85% depending on the reaction conditions.

About

CAS No 72869-69-3
English Name 1-(2-(alpha-(p-Chlorophenyl)-alpha-methylbenzyloxy)ethyl)piperidine
Molecular Formula C21H26ClNO
Molecular Weight 343.89 g/mol
SMILES ClC1C=CC(=CC=1)C(C)(C1C=CC=CC=1)OCCN1CCCCC1
InChIKey ZBQFYVCEMFKBLW-UHFFFAOYSA-N
Last Updated: 2026-03-01 17:12

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