Compound Q&A
How is Anastrozole EP Impurity D (CAS: 1027160-12-8) typically synthesized?
Answer
Anastrozole EP Impurity D (CAS: 1027160-12-8) is synthesized via a multistep process involving amidation and reduction reactions. Commonly, this involves the amidation of 4-methyl-2,6-dichlorophenol with an appropriate amine followed by selective reduction to form the desired impurity. This process requires precise control over reaction conditions to achieve high yield and selectivity.
About
CAS No
1027160-12-8
English Name
Anastrozole EP Impurity D
Molecular Formula
C15H16Br2N2
Molecular Weight
384.11 g/mol
SMILES
CC(C)(C#N)c1cc(cc(c1)C(C)(C)C#N)C(Br)Br
InChIKey
AJUNARPIHUBZNV-UHFFFAOYSA-N
Last Updated: 2026-01-13 15:28
