Compound Q&A
How is Methyl 1-(5-bromo-2-pyrimidinyl)cyclopropanecarboxylate (CAS: 1447607-69-3) typically synthesized?
Answer
Methyl 1-(5-bromo-2-pyrimidinyl)cyclopropanecarboxylate (CAS: 1447607-69-3) can be synthesized through a multi-step process involving the bromination of 2-pyrimidinylcyclopropanecarboxylic acid methyl ester followed by coupling with bromine. The reaction is typically carried out under anhydrous conditions and may require the use of a catalyst such as N,N-dimethylaminopyridine (DMAP). The overall yield is generally good, and the reaction is known for its high selectivity.
About
CAS No
1447607-69-3
English Name
Methyl 1-(5-bromo-2-pyrimidinyl)cyclopropanecarboxylate
Molecular Formula
C9H9BrN2O2
Molecular Weight
257.087 g/mol
SMILES
COC(=O)C1(CC1)c2ncc(cn2)Br
InChIKey
HZNFYESIZQQWCI-UHFFFAOYSA-N
Last Updated: 2026-01-13 15:28
