Compound Q&A
How is 1-Methyl-5-oxoproline (CAS: 72442-37-6) typically synthesized?
Answer
1-Methyl-5-oxoproline can be synthesized through the condensation of methyl acrylate and oxoacetic acid. The reaction typically proceeds with the use of a base catalyst such as sodium hydride. The yield is generally around 70-75%, and the selectivity towards the desired product is high. This compound can also be prepared by the dehydration of 1-methyl-5-oxoproline-2-carboxylic acid.
About
CAS No
72442-37-6
English Name
1-Methyl-5-oxoproline
Molecular Formula
C6H9NO3
Molecular Weight
143.14 g/mol
SMILES
CN1C(CCC1=O)C(=O)O
InChIKey
SHLYZEAOVWVTSW-UHFFFAOYSA-N
Last Updated: 2026-01-13 06:10
