Compound Q&A

How is [2-Hydroxy-3-[2-hydroxy-3-[2-hydroxy-3-[2-hydroxy-3-[2-hydroxy-3-[2-hydroxy-3-[(Z)-octadec-9-enoyl]oxypropoxy]propoxy]propoxy]propoxy]propoxy]propyl] (Z)-octadec-9-enoate (CAS: 76009-37-5) typically synthesized?

Answer

[2-Hydroxy-3-[2-hydroxy-3-[2-hydroxy-3-[2-hydroxy-3-[2-hydroxy-3-[2-hydroxy-3-[(Z)-octadec-9-enoyl]oxypropoxy]propoxy]propoxy]propoxy]propoxy]propyl] (Z)-octadec-9-enoate
This compound is synthesized through a series of Michael addition reactions involving a cyclic enone and a reducing agent followed by esterification. The key steps involve the use of a zinc amalgam reduction to form the corresponding alcohol, and then subsequent Michael addition reactions with cyclic enone derivatives, followed by esterification with octadec-9-enoic acid. The overall yield is moderate, around 50-60%, and the selectivity is high.

About

CAS No 76009-37-5
English Name [2-Hydroxy-3-[2-hydroxy-3-[2-hydroxy-3-[2-hydroxy-3-[2-hydroxy-3-[2-hydroxy-3-[(Z)-octadec-9-enoyl]oxypropoxy]propoxy]propoxy]propoxy]propoxy]propyl] (Z)-octadec-9-enoate
Molecular Formula C54H102O15
Molecular Weight 991.38 g/mol
SMILES O(CC(COCC(COCC(COCC(COCC(COCC(COC(CCCCCCC/C=C\CCCCCCCC)=O)O)O)O)O)O)O)C(CCCCCCC/C=C\CCCCCCCC)=O
InChIKey HWZAMIRTDQUMNN-CLFAGFIQSA-N
Last Updated: 2026-01-08 21:12

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