Compound Q&A
How is 5,6-Dichloro-1-[1-(4-chlorobenzyl)-4-piperidinyl]-1,3-dihydro-2H-benzimidazol-2-one (CAS: 2134602-45-0) typically synthesized?
Answer
![5,6-Dichloro-1-[1-(4-chlorobenzyl)-4-piperidinyl]-1,3-dihydro-2H-benzimidazol-2-one](https://static.chemtradehub.com/structs/213/2134602-45-0-7d10.webp "5,6-Dichloro-1-[1-(4-chlorobenzyl)-4-piperidinyl]-1,3-dihydro-2H-benzimidazol-2-one")
5,6-Dichloro-1-[1-(4-chlorobenzyl)-4-piperidinyl]-1,3-dihydro-2H-benzimidazol-2-one is synthesized via a multi-step process involving the reaction of 4-chlorobenzyl chloride with 4-piperidone and subsequent benzimidazolization. The synthesis requires careful control of reaction conditions and the use of appropriate catalysts and solvents. The overall yield is moderate, around 50-60%, and the process involves several purification steps to obtain the desired compound.
About
CAS No
2134602-45-0
English Name
5,6-Dichloro-1-[1-(4-chlorobenzyl)-4-piperidinyl]-1,3-dihydro-2H-benzimidazol-2-one
Molecular Formula
C19H18Cl3N3O
Molecular Weight
410.73 g/mol
SMILES
c1cc(ccc1CN2CCC(CC2)n3c4cc(c(cc4[nH]c3=O)Cl)Cl)Cl
InChIKey
LAGUDYUGRSQDKS-UHFFFAOYSA-N
Last Updated: 2026-01-08 21:12
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