Compound Q&A
How is 4-Chloro-1,2-dihydro-3H-indazol-3-one (CAS: 787580-87-4) typically synthesized?
Answer
4-Chloro-1,2-dihydro-3H-indazol-3-one can be synthesized via a multi-step process involving the condensation of 2-aminoindazol-3-one with thiochloroacetic acid, followed by acid hydrolysis. The reaction involves the use of a Lewis acid as a catalyst to promote the condensation step. The overall yield is moderate, and the method provides good selectivity for the desired product.
About
CAS No
787580-87-4
English Name
4-Chloro-1,2-dihydro-3H-indazol-3-one
Molecular Formula
C7H5ClN2O
Molecular Weight
168.58 g/mol
SMILES
C1=CC2=C(C(=C1)Cl)C(=O)NN2
InChIKey
KLRONPGJZULTOP-UHFFFAOYSA-N
Last Updated: 2026-01-08 21:12
