Compound Q&A

How is 1-(5-Methyl-2-thienyl)-1-propanone (CAS: 59303-13-8) typically synthesized?

Answer

1-(5-Methyl-2-thienyl)-1-propanone
1-(5-Methyl-2-thienyl)-1-propanone (CAS: 59303-13-8) is typically synthesized by the condensation of 5-methylthiophenol with formaldehyde in the presence of a base such as sodium hydroxide. The reaction involves the formation of an acyloin intermediate which then undergoes dehydration to form the desired ketone. The yield and selectivity can be optimized using appropriate conditions and catalysts.

About

CAS No 59303-13-8
English Name 1-(5-Methyl-2-thienyl)-1-propanone
Molecular Formula C8H10OS
Molecular Weight 154.23399999999995 g/mol
SMILES CCC(=O)C1=CC=C(S1)C
InChIKey ROPOMQPSWIOWSN-UHFFFAOYSA-N
Last Updated: 2026-01-08 21:12

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