Compound Q&A
How is N-[3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]benzamide (CAS: 1330596-14-9) typically synthesized?
Answer
![N-[3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]benzamide](https://static.chemtradehub.com/structs/133/1330596-14-9-9905.webp "N-[3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]benzamide")
N-[3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]benzamide is typically synthesized through Suzuki coupling reactions. This involves the coupling of a boronic acid derivative with a phenyl benzamide in the presence of a palladium catalyst, such as Pd(PPh3)4, and a base like potassium carbonate, under microwave conditions. The reaction yields the target compound with good selectivity and high yield.
About
CAS No
1330596-14-9
English Name
N-[3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]benzamide
Molecular Formula
C19H22BNO3
Molecular Weight
323.2 g/mol
SMILES
O=C(c1ccccc1)Nc1cccc(c1)B1OC(C(O1)(C)C)(C)C
InChIKey
YRVJWHIVVDYOFP-UHFFFAOYSA-N
Last Updated: 2026-01-07 14:58
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