Compound Q&A
How is 2-(Chloromethyl)-5-methyl-1,3-benzoxazole (CAS: 41014-44-2) typically synthesized?
Answer
2-(Chloromethyl)-5-methyl-1,3-benzoxazole can be synthesized via the condensation of 4-chloromethyl-1,3-benzoxazol-2(3H)-one with methylamine. The reaction is typically carried out in the presence of a base like sodium hydroxide in an aprotic solvent like dimethylformamide (DMF). The yield and selectivity of the product can be enhanced by optimizing reaction conditions and using appropriate catalysts.
About
CAS No
41014-44-2
English Name
2-(Chloromethyl)-5-methyl-1,3-benzoxazole
Molecular Formula
C9H8ClNO
Molecular Weight
181.62 g/mol
SMILES
CC1=CC2=C(C=C1)OC(=N2)CCl
InChIKey
HLMSMIKJAZQYJS-UHFFFAOYSA-N
Last Updated: 2026-01-07 14:58
