Compound Q&A
How is 4,6-Difluoro-2-methyl-1H-benzimidazole (CAS: 874814-18-3) typically synthesized?
Answer
4,6-Difluoro-2-methyl-1H-benzimidazole can be synthesized via the condensation of 2-methylbenzaldehyde with 1,3-difluorobenzene in the presence of a Lewis acid catalyst, such as aluminum chloride, at a temperature of around 100°C. The reaction proceeds with high selectivity and yield, producing the desired product with minimal by-products.
About
CAS No
874814-18-3
English Name
4,6-Difluoro-2-methyl-1H-benzimidazole
Molecular Formula
C8H6F2N2
Molecular Weight
168.15 g/mol
SMILES
CC1=NC2=C(N1)C=C(C=C2F)F
InChIKey
ABQYTBKFUCHTOG-UHFFFAOYSA-N
Last Updated: 2026-01-07 14:58
