Compound Q&A

How is 1,2,3,4-Tetrahydro-5-quinolinol (CAS: 61468-43-7) typically synthesized?

Answer

1,2,3,4-Tetrahydro-5-quinolinol
1,2,3,4-Tetrahydro-5-quinolinol is commonly synthesized via the reduction of 5-quinolinecarboxylic acid or through the condensation of aldehyde and amines. The synthesis often involves the use of lithium aluminum hydride (LAH) as a reducing agent, yielding a 90% yield. The reaction is typically carried out in anhydrous ether under an inert atmosphere.

About

CAS No 61468-43-7
English Name 1,2,3,4-Tetrahydro-5-quinolinol
Molecular Formula C9H11NO
Molecular Weight 149.19 g/mol
SMILES Oc1cccc2NCCCc12
InChIKey AACROBBFQRNFHE-UHFFFAOYSA-N
Last Updated: 2026-01-07 14:58

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