Compound Q&A
How is 5-(1-Piperazinyl)-2-Benzofurancarboxylic Acid Ethyl Ester Dihydrochloride Hydrate (CAS: 1422956-31-7) typically synthesized?
Answer
5-(1-Piperazinyl)-2-Benzofurancarboxylic Acid Ethyl Ester Dihydrochloride Hydrate is commonly synthesized via a multi-step process involving the esterification of 2-benzofurancarboxylic acid ethyl ester with piperazine, followed by hydrochloric acid treatment to form the dihydrochloride salt. The reaction is typically carried out in a solvent such as ethanol or dichloromethane, with catalysis by a strong acid like sulfuric acid to improve yield and selectivity.
About
CAS No
1422956-31-7
English Name
5-(1-Piperazinyl)-2-Benzofurancarboxylic Acid Ethyl Ester Diydrochloride Hydrate
Molecular Formula
C15H22Cl2N2O4
Molecular Weight
365.25 g/mol
SMILES
CCOC(=O)c1cc2c(o1)ccc(c2)N1CCNCC1.O.Cl.Cl
InChIKey
GOKCUPVWRIMFNJ-UHFFFAOYSA-N
Last Updated: 2026-01-07 10:17
