Compound Q&A

How is 5-Methoxy-2-(trifluoromethyl)benzaldehyde (CAS: 944905-42-4) typically synthesized?

Answer

5-Methoxy-2-(trifluoromethyl)benzaldehyde
5-Methoxy-2-(trifluoromethyl)benzaldehyde (CAS: 944905-42-4) is typically synthesized via the method of coupling 2-(trifluoromethyl)benzaldehyde with methanol in the presence of a suitable base like sodium methoxide. The reaction is conducted in a solvent such as methanol or dimethylformamide. The yield is usually around 70-80%, and the product can be isolated by recrystallization from an appropriate solvent.

About

English Name 5-Methoxy-2-(trifluoromethyl)benzaldehyde
Molecular Formula C9H7F3O2
Molecular Weight 204.14699999999993 g/mol
SMILES COc1ccc(c(c1)C=O)C(F)(F)F
InChIKey QFKMLBPPJRRDBX-UHFFFAOYSA-N
Last Updated: 2026-01-07 05:52

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